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Duke ALS Clinic

Morreene Road

The Duke ALS Clinic is a multidisciplinary clinic dedicated toward providing amyotrophic lateral sclerosis (ALS) patients with compassionate, state-of-the-art care and researching new treatments for this devastating disease. We are located at the Duke Neurological Disorders Clinic on 932 Morreene Road in Durham.

ALS is a tough disease. It calls for an organized aggressive approach. We start by confirming the diagnosis and excluding ALS mimics. If ALS is confirmed we use the latest disease modifying therapies to slow progression. Our multi-disciplinary team identifies specific symptoms and problems and provides a wide range of options for dealing with them. We are always on the lookout for new therapies in our active research program. All of us here are enthusiastic and hopeful!

Our Team

The Duke ALS clinic includes a team of clinical experts that work together to provide our patients with a variety of care. This team includes:

  • a pulmonologist and respiratory therapist to monitor breathing abilities and help patients breathe better and more comfortably
  • a physician assistant to perform physician examinations, assess and treat symptoms, manage symptoms, and provide counseling
  • physical therapists to provide exercises, education, and problem solving to help patients and their carers with mobility and safety
  • occupational therapists to help patients maintain their ability to participate in everyday activities such as eating, dressing, bathing, and using the computer.
  • speech therapists and rehabilitation engineers to address slurred speech and swallowing problems
  • a dietitian to help patients reach and maintain a healthy diet and eating habits
  • a medical social worker to provide screening, assessment and intervention to patients and their families, empowering them to deal with the stresses that accompany a diagnosis of ALS
  • a clinical research nurse coordinator to assist with clinical trials
  • assistive technology professionals who provide wheelchairs and other equipment, as well as education and training
  • ALS Association care service representatives, who help patients and families cope with the day-to-day challenges of living with ALS by providing a variety of services both in the clinic setting and the community.


BedlackOur Tele-ALS program allows us to stay connected with our current North Carolina-based ALS patients who can no longer travel. We use a secure teleconferencing program which links our office directly to their homes.

Patients participating in the program receive help managing symptoms, order or repair symptoms, and stay informed about new research developments. Together these steps can make a huge difference. Download instructions for how to start a telehealth video visit here.


The Duke ALS clinic has an active research program which includes clinical trials of medications to slow ALS or improve symptoms, as well as studies examining ALS epidemiology, genetics, and basic science.

Our clinic director also leads the international ALSUntangled program for reviewing alternative and off-label ALS treatments, and the patient- and family-funded ALS Reversals program, which attempts to understand why some patients with ALS get better and to make this happen more often.

The following clinical trials are ctively recruiting ALS patients at Duke:


Requests for new appointments may be made by referring physicians or by patients themselves. We strive to get new patients seen quickly. Incomplete referring information and lack of outside records will significantly delay getting an appointment.

To schedule an appointment, use this form.

Please arrive at least 30 minutes early to the clinic for check in. Bring records to your appointment, including clinic notes, imaging studies, blood tests, and EMG reports. Bring all the medications you are taking.

How to Help

Hopefully, you have seen that this is a special clinic with unique services and opportunities. Many of the clinical services provided are not billable. While there are a lot of exciting ideas for new ALS research projects, funding for them is getting tougher to find. Outside contributions to the clinic are thus necessary and greatly appreciated. Some ideas for contributions include:

  • Donate to the Duke ALS Clinic online through the secure Duke Charitable Gifts website. Use the "Add an unlisted designation" link to specify a donation directly to the Duke ALS Clinic.
  • Send a check made payable to Duke ALS Clinic, and mail it to: Duke ALS Clinic, 932 Morreene Road, Durham, NC 27705.
  • Donate equipment back to the Clinic if it is not being used. It can be added to our loan program, which provides necessary equipment to those with ALS.
  • If a friend or loved one passes from ALS, request donations be made to the clinic in lieu of flowers.
  • Donate your old cell phone, digital camera, iPod or tablet to be recycled and benefit the Duke ALS Clinic as the charity of your choice! Information and instructions for starting a donation program at your office or home can be found online at Recycling for Charities.
  • Donate your old car to the Duke ALS Clinic. This provides a tax break for you and much-needed research funds for us!

Call Stacey Asnani at 919-668-2875 for more information on how you can help.