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Chiba-Falek Lab

Photo of Ornit Chiba-Falek

Ornit Chiba-Falek

Office: Bryan Research Building, 201A
Campus mail: 311 Research Drive, Durham, NC 27710
Phone: 919-681-8001
Fax: 
919-613-6448
Email: o.chibafalek@duke.edu

Genetics plays an incredibly complex role in how neurodegenerative diseases like Alzheimer’s and Parkinson’s diseases appear and develop. Even small changes in the DNA sequence and structure can directly alter the protein product of a gene, or change how, when, and/or where a gene or a group of genes are expressed; these effects determine whether a disease will occur, when it happens, and the extent of its symptoms. Our research attempts to better understand the genetic processes underpinning age-related neurodegenerative diseases, in particular Alzheimer’s disease, related dementia, and Lewy body spectrum disorders.