The laboratory of Dr. Chiba-Falek in the Department of Neurology and the Center of Genomic and Computational Biology at Duke University Medical Center is seeking a highly-motivated postdoctoral associate who is interested to study the genetic architecture and molecular mechanisms underlying late onset Alzheimer’s disease and cognitive decline in aging. Applicants will be considered for an exciting newly funded project that brings together neuroscience and innovative genomic technologies. Areas of interest include Alzheimer’s disease etiologies, functional genomics, gene expression, chromatin remodeling, genetic biomarkers and target discovery. The project involves observational studies in human brain tissues complemented by bioinformatics analyses and experiments using iPSC-derived model systems. The ideal applicant will have a strong background in genetics, molecular and cellular biology.
This position requires excellent basic cellular / molecular skills, including experience with genomic technologies, gene expression analyses, cells culture specifically iPSC, genome editing, transfection/transformation, PCR, ELISA/Western blot analysis, FACS, LCM and molecular cloning. A strong background in human genetics and neuroscience is also required. Experience in bio-informatics is a plus.
The candidate must be able to function in a fast-paced environment, manage multiple tasks, be flexible to rapidly changing priorities and learn new techniques. Excellent verbal and written communication skills, scientific creativity, and the ability to work both independently and in a team environment are important.
A recent PhD (who have less than 2 years of research experience after receipt of their doctorate degree) is preferred.
Interested candidates with a relevant background should email CV with a brief cover letter describing research accomplishments, future research goals and contact information of three professional references to Dr. Ornit Chiba-Falek at firstname.lastname@example.org.