The Chiba-Falek lab is seeking candidates for the following positions:
Research Technician I
The candidate will perform a variety of technical duties involved in conducting standardized tests, experiments and determinations in support of research-oriented activities at Duke University.
- Perform a variety of technical duties involved in conducting physical, chemical or biological tests, experiments, and determinations to obtain data in support of research-oriented activities; compile and document procedures and results.
- Set up instruments, material, and apparatus and operate standard laboratory equipment required for specific tests.
- Operate various electronic devices in the collection, tabulation, and calculation of data.
- Obtain, prepare, mount and stain tissue, blood and other substances for microscopic examinations.
- Prepare culture media, chemicals, reagents, and solutions.
- Assist in the development of new research procedures and techniques
- Maintain sufficient inventory of materials, supplies and equipment for performance of duties; clean and maintain standard laboratory equipment.
- Review work of lower level laboratory personnel and assist in the training of new personnel.
- Maintain inventory records.
- Generate report of experimental results.
- Generate electronic versions of the lab’s protocols and procedures.
Research Technician II
The candidate will perform a variety of complex technical duties involved in conducting laboratory tests, experiments and determinations in support of Duke University research operations.
• Performs a variety of complex technical duties involved in conducting physical,chemical, biological and other research laboratory tests, experiments and determinations to obtain data for research purposes;compile, analyze, document and draw tentative conclusions from experimental results.
• Confer with the principal investigator to review work assignments and develop plans for research experiments; make minor modifications to existing laboratory procedures and techniques to meet the needs of the particular equipment as required.
• Review laboratory methods manual, scientific journals, abstracts, and other literature for information applicable to research experiments.
• Determine and setup instruments, material, and apparatus and operate laboratory equipment required for specific tests.
• Obtain, prepare, mount and stain tissue, blood and other substances for microscopic examination.• Prepare culture media, chemicals, reagents and solutions.
• Maintain sufficient inventory of material, supplies, and equipment for performance of duties; clean and maintain laboratory equipment.
• Review work of lower-level laboratory personnel within designated areas and assist in training new personnel.
• Perform other related duties incidental to the work described herein.
• Review completeness or accuracy of the work of others
• Give recommendations, advice or guidance to others
• Review expenses related to materials and supply, and confirm the grant-budget monthly reports.
• Generating reports of results
• Create and maintain laboratory records. (protocols and biological materials).
The laboratory of Dr. Chiba-Falek in the Department of Neurology and the Center of Genomic and Computational Biology at Duke University Medical Center is seeking a highly motivated postdoctoral associate who is interested to study the genetic architecture and molecular mechanisms underlying late onset Alzheimer’s disease and cognitive decline in aging. Applicants will be considered for an exciting newly funded project that brings together neuroscience and innovative genomic technologies. Areas of interest include Alzheimer’s disease etiologies, functional genomics, gene expression, chromatin remodeling, genetic biomarkers and target discovery. The project involves observational studies in human brain tissues complemented by bioinformatics analyses and experiments using iPSC-derived model systems. The ideal applicant will have a strong background in genetic, molecular, and cellular biology.
This position requires excellent basic cellular / molecular skills, including experience with genomic technologies, gene expression analyses, cells culture specifically iPSC, genome editing, transfection/transformation, PCR, ELISA/Western blot analysis, FACS, LCM and molecular cloning. A strong background in human genetics and neuroscience is also required. Experience in bio-informatics is a plus.
The candidate must be able to function in a fast-paced environment, manage multiple tasks, be flexible to rapidly changing priorities and learn new techniques. Excellent verbal and written communication skills, scientific creativity, and the ability to work both independently and in a team environment are important.
A recent PhD (who have less than 2 years of research experience after receipt of their doctorate degree) is preferred.
Interested candidates with a relevant background should email CV with a brief cover letter describing research accomplishments, future research goals and contact information of three professional references to Dr. Ornit Chiba-Falek at firstname.lastname@example.org. They should also apply through the official Duke system here (Duke Jobs Req 401517802.)