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Joseph and Kathleen Bryan Alzheimer's Disease Research Center


The Joseph and Kathleen Bryan Alzheimer's Disease Research Center  is a clinical and basic research science center dedicated to caring for patients and families affected by Alzheimer's disease (AD) and other memory disorders, discovering the basic mechanisms underlying the disease process, and developing effective treatments and preventive strategies for AD and related conditions.

Who we are

The Bryan ADRC was one of the 10 original Alzheimer's Disease Centers (ADC) funded by the National Institute on Aging (NIA). Established in 1985, the Bryan ADRC has led research and delivered state-of-the-art care for people with Alzheimer's disease (AD) and their families. Outpatient specialty services are provided through the Center's Memory Disorders Clinic (MDC).

What we do

In addition to its clinical and basic research activities, our center offers support services, community outreach, and education programs for families caring for persons with memory disorders. We share scientific and clinical findings with the general public, the medical and scientific community via publications, an annual conference, and clinical training programs.

We also advance basic medical discovery about AD and related diseases. Our basic science mission is facilitated through the DNA cell repository located in the Duke Molecular Physiology Institute (DMPI) and the Kathleen Price Bryan Brain Bank. These affiliated programs provide an invaluable source of DNA and fresh brain tissue, which can be sent to laboratories across the globe to hasten research and generate new ideas through interdisciplinary collaboration.

We also improve the diagnosis, care, and treatment for AD patients and translates genetic and other basic science discoveries into practical treatments and disease prevention. Under the guidance of Director Kathleen Welsh-Bohmer, PhD, and Associate Director Jim R. Burke, our center includes faculty from the Duke Departments of Medicine, Psychiatry, Psychology, Pathology, Genetics, Neurobiology, Radiology, and Anesthesiology.

How we work

Our research efforts are supported by the National Institute on Aging, large and small private gifts from families and supporters, the Alzheimer's Association, and collaborations with pharmaceutical companies here in Research Triangle Park. We thank our many supporters and especially our many research participants. The private monetary gifts and the non-monetary gifts of time, effort, and brain donations have played a pivotal role in the advances in Alzheimer's research.