News

Over the course of a few days in late September of 2021, Carol Cerase of Lumberton, NC, experienced increasing weakness in her legs, trouble swallowing, and several falls. Doctors at her local hospital couldn’t find the cause, so they reached out to Duke Health’s neurology experts, who diagnosed Cerase with Guillain-Barré syndrome (GBS). Duke’s team recommended plasma exchange therapy to stop the disease’s progression and allow the nerves to heal. “I was lucky I got the treatment so fast,” said Cerase. “I think it saved me.”

This October, members of the Duke Neurology Department contributed to 12 new peer-reviewed journal articles, advancing our understanding of Alzheimer’s disease, stroke, chronic pain, and other conditions. These articles include discussions of the best framework for neuroscience curricula for medical students, the discovery of an existing experimental drug which offers a new avenue for treating pain without potential addiction issues, and an examination of the viability of ketogenic diets as an alternative treatment for amyotrophic lateral sclerosis (ALS).

Members of the Duke Neurology Department contributed to seventeen peer-reviewed research studies published this August. Members of the lab of Nicole Calakos, MD, PhD, discovered that a medication created to treat patients with HIV may help people with dystonia. New translational research provided the most accurate atlas of the mouse model to date and answered questions about late-onset Alzheimer’s disease.

This July, new research from the Duke Neurology Department answered questions about the subcellular origins of itching, how COVID-19 is affecting people with amyotrophic lateral sclerosis, what factors influence people eligible for epilepsy surgery to move forward with the procedure and topics. The paragraphs below summarize the 11 articles appearing in peer-reviewed publications from our faculty, staff, and trainees. Check them out and find links to the original publications below.

Neuromuscular Disease

New publications written by members of the Duke Neurology Department published this June advanced our understanding of the origins of Alzheimer’s disease, stroke, and spinal injuries, as well as offering new insights on how to better diagnose and treat these and other conditions. Our faculty contributed to recent articles in Lancet Neurology, Stroke, and other high-impact journals. Read more about each of these stories, and find links to the original articles themselves, in the paragraphs below.
 

Neuromuscular Disease

When Zaeem Siddiqi MD, PhD, joined the neurology program at the University of Alberta after completing his residency and fellowship at Duke, he had just one other colleague specializing in neuromuscular disease. Now that team has expanded to five, with more on the way. For this week’s “Spotlight” interview, Siddiqi talks to us about his current work treating patients from Edmonton to Kagluktuk near the arctic circle while training neurologists and conducting research on myasthenia gravis.

Members of the Duke Neurology Department did their part for Stroke Awareness Month, contributing to eight new peer-reviewed studies published this May. But our other divisions didn’t hold back either, with thirteen other articles advancing our understanding of neuro-oncology, multiple sclerosis, headache, and other subjects.

Read about each of the studies published from members of the Duke Neurology Department below, and find links to the original journal articles as well.

Stroke

The American Academy of Neurology (AAN) has moved its annual meeting to a virtual setting this year, but its offerings of the latest education and scientific programming continue. This year, members of the Duke Neurology Department collaborated with their colleagues at Duke and with other academic institutions to advance our understanding of neuro-oncology, myasthenia gravis, ALS, and other fields and disciplines. 

Members of the Duke Neurology Department contributed to 21 new studies in peer-reviewed journals this March, advancing our ability to understand, treat, and prevent diseases and conditions from across the field of neurology. Brian Mac Grory, MB BCh, MRCP, and other members of our stroke and vascular neurology helped answer questions about the best way to treat patients who have a stroke in their sleep.

Sarah Parker, MSN, AGPCNP-BC, got her first direct exposure to neurological injuries as a high school student, after her brother suffered a mild traumatic brain injury. His altered state, disrupted memory and long but productive road to recovery fascinated Parker, who eventually joined our neurology unit in Duke University Hospital. Several years and a master’s degree later, Parker is rejoining neurology in a dual role that combines research and clinical work in our ALS Clinic on Morreene Road.