Parkinson's Disease And Movement Disorders News

A new blood-based test for Parkinson’s disease, improved monitoring techniques for epilepsy, and a chapter discussing the use of transcranial magnetic stimulation (TMS) as a noninvasive treatment for dystonia are just a few examples of the latest research from members of the Duke Neurology Department.

Local middle school students visited Duke this August to touch human brains, learn about the U.S. health system, and watch research being conducted in real time, thanks to the BOOST (Building Opportunities and Overtures in Science and Technology) program and the Duke Neurology Department.

A promising new therapy for brain tumors detailed in the New England Journal of Medicine and a  validation of a popular stroke treatment for patients taking vitamin K antagonists published in JAMA are just two highlights of the 15 peer-reviewed journal articles authored by members of the Duke Neurology Department this June. 

What do analyses of stroke rehabilitation techniques, new therapeutic targets for jaw pain, and guidelines to help sleep apnea patients cope with runny noses have in common? They’re all subjects of articles published by members of the Duke Neurology Department this April. Read the summaries below to learn more about the nine peer-reviewed journal articles members of the Duke Neurology Department contributed to over the past 30 days, and find links to the original research below.

Members of the Duke Neurology Department shared their advances and insights in neurology education, health disparities, movement disorders, and other areas at the American Academy of Neurology’s (AAN) 75th annual meeting in Boston this week. This year, our faculty, staff, and trainees contributed more to the AAN than in any previous year, contributing to 20 posters and abstracts and six classes or sessions.

The American Society for Clinical Investigation (ASCI) has awarded Nicole Calakos, MD, PhD, its 2023 Stanley J. Korsmeyer Award. The Korsmeyer Award recognizes outstanding achievements of ASCI members in advancing knowledge and mentoring future generations of life science researchers. Calakos received this award for her contributions to understanding basal ganglia physiology and its involvement in diseases such as compulsive behavior and movement disorders.

The American Society for Clinical Investigation (ASCI) has selected Nicole Calakos, MD, PhD as the recipient of the 2023 ASCI/Stanley J. Korsmeyer Award. She is recognized for her contributions to the understanding of brain plasticity and for her discovery of a signaling defect shared by several causes of dystonia. Dr. Calakos is a Professor of Neurology, Neurobiology, and Cell Biology at Duke University Medical Center; the Lincoln Financial Group Distinguished Professor of Neurobiology; and a member of the US National Academy of Medicine.

Managing research projects for one academic laboratory can be challenging on its own. Oula Khoury, PhD, the subject of our latest Spotlight interview, has to juggle projects for five at Duke (plus one more at Stanford) as part of an Aligning Science Across Parkinson’s (ASAP) initiative. Khoury talks to us about her work managing timelines, experiments, and budgets for these projects in an effort to learn more about neurons’ vulnerability to Parkinson’s.

The consequences of Parkinson’s disease and other neurodegenerative movement disorders go beyond their physical symptoms. They also force people with these conditions, as well as their loved ones, to confront grief, anger, and a host of end-of-life concerns. Katherine Henderson, MDiv, the subject of this week’s Spotlight interview, recently joined our interdisciplinary Benchmark Clinic as a non-denominational chaplain to help Parkinson’s patients confront and work through these concerns.

Rabia Ghazi, MBBS, first became interested in neurology when she saw how neurologists used examination findings, neuroanatomy, and clinical history to diagnose and treat complex neurological conditions. She decided to pursue movement disorders when she saw the difference deep brain stimulation (DBS) and other therapies were able to make in people’s lives. Now, she’s finishing the second of a two-year fellowship in the field, and preparing for a career that involves both clinical care and research.