News

New publications written by members of the Duke Neurology Department published this June advanced our understanding of the origins of Alzheimer’s disease, stroke, and spinal injuries, as well as offering new insights on how to better diagnose and treat these and other conditions. Our faculty contributed to recent articles in Lancet Neurology, Stroke, and other high-impact journals. Read more about each of these stories, and find links to the original articles themselves, in the paragraphs below.
 

Neuromuscular Disease

Clinical trials contain many complicated moving parts. Randy Smith, MPH, a clinical research coordinator who recently joined our Department, is working to make these parts move as smoothly as possible for a post-stroke recovery clinical trial. For this week’s “Spotlight” interview, Smith talks to us about how she came to Duke, how her previous experience as a dietitian influences her current work, and enjoying tennis, knitting, and volunteering for Meals on Wheels when she’s not at Duke.

Thirteen years ago, Matthew Tackitt was working in the financial sector, when the 2008 global economic crisis and cross-country move got him thinking about a career change. He opted for nursing and has stuck with it ever since. This May, Tackitt joined the Movement Disorders clinic as their navigator for their Deep Brain Stimulator (DBS) Program.

A novel application of zoledronic acid, a bisphosphonate typically prescribed to prevent or treat osteoporosis, is being assessed in a large-scale trial for its potential to prevent fractures in senior patients with Parkinson’s Disease (PD).

Treatment for movement disorders goes beyond providing medical care. Adjusting to a life with Parkinson’s, Huntington’s, or other conditions requires requires lifestyle changes, planning for the future, and coping with the stress and waves of emotions associated with a diagnosis. Anne Kosem, LCSW, at our Morreene Road Clinic helps people with movement disorders and their loved ones navigate these and other complex challenges.

Members of the Duke Neurology Department advanced the fields of clinical, translational, and basic neuroscience this April with 14 new peer-reviewed studies. Nicole Calakos, MD, PhD, was the senior author of a new study in Science that  expands our understanding of the integrated stress response in the brain and how it influences learning and memory.

Daniel Gingerich joined the laboratory of Ornit Chiba-Falek, PhD, last year, exactly two days before the COVID-19 pandemic forced a campus-wide shut down, forcing him to learn a new set of technical skills from home. Since then Gingerich has become proficient in single-cell data analysis, and is using those techniques to better understand genetic and epigenetic dysregulation in late onset Alzheimer's disease.

Abbie Suttle, MSc, wants to improve our understanding of pain. In the lab of Yong Chen, PhD, she is currently working on two projects, the first to better understand the  trigeminal ganglion to potentially treat a painful jaw disorder known as TMD, and another to better understand and prevent the sensitization process that makes medications for migraine and headache less effective over the long term. In this week’s Spotlight interview, Suttle talks to us about her involvement in both of these projects.

As our financial services advisor, Matthew Burger works to make sure all neurology patients at our Morreene Road and 1L Clinics have the best and most appropriate financial resources to help meet their needs. For this week’s “Spotlight” interview, Burger talks to us about how he and his colleagues are able to assist patients, his history before coming to Duke, and looking forward to traveling and life without a mask once the COVID-19 pandemic is over. 

This week’s “Spotlight” interview shines on Melanie McBroom, MS, EMT-NC, neurodiagnostic technician within the EMG lab in our 1L clinic. McBroom talks to us about her work helping patients with carpal tunnel syndrome, ALS, and other conditions. She also discusses how her master’s degree and experience as an EMT inform her work, the most difficult and enjoyable parts of her job, and looking forward to not having to wear a mask when the COVID-19 pandemic is over.