Duke Neurology Research Round Up, June 2022

Members of the Duke Neurology Department contributed to 13 new peer-reviewed journal articles this May, advancing our understanding of how viruses that kill cancer cells may be used against brain tumors, the optimal treatments for various types of stroke, the origins of Parkinson’s disease, and more. Read the paragraphs below for summaries of our research from the past 31 days, as well as links to the complete articles themselves.

Hospital Neurology

Duke Neurology Research Round Up, April 2022

This March, members of our Department contributed to studies that reveal potential new therapeutic targets for Alzheimer’s disease, help triage patients suffering from traumatic brain injury, address issues contributing to physician burnout, and more. In all, our faculty, staff, students, and trainees contributed to 15 studies published over the past 31 days. Read about them and find links to the original articles below.

Parkinson’s and Movement Disorders

Postdoc Spotlight: Zhiyong Liu, PhD

Zhiyong Liu, PhD, learned about the devastating effects neurodegenerative diseases have on patients and their families firsthand during his senior year of college, when he worked in a clinical research lab. Now, as a postdoctoral associate within the lab of Andy West, PhD, he’s performing translational research to develop new treatments for one of those conditions, Alzheimer’s disease. In this week’s “Spotlight” interview, Liu talks about the focus of his work, his recent K99/R00 award, and enjoying running, fishing, and time with his family when he’s not at work.

Duke Neurology Research Round Up, March 2022

This February, new research from members of the Duke Neurology Department advanced our understanding of the treatment of stroke, brain tumors and amyotrophic lateral sclerosis (ALS) as well as the genetics and origins of Alzheimer’s disease. The 13 journal articles written or co-written by members of our faculty include publications in JAMA, Neurology, the British Medical Journal, and other publications. Read summaries of those studies, and find links to the original articles, in the paragraphs below.


Staff Spotlight: Clare Essex

Professionally, Clare Essex lives in two worlds. Within the lab of Laurie Sanders, PhD, and Carol Colton, PhD, in the Duke Neurology Department, she’s working part-time to improve understandings the genetic underpinnings of neurodegenerative disease. Essex spends the other half of her work week as a medical scribe at UNC REX Hospital in Raleigh.

Duke Neurology Research Round Up, February 2022

The first month of 2022 saw the publication of 18 new peer-reviewed journal articles from members of the Duke Neurology Department. Highlights include a new article in Lancet Neurology discussing the epidemiology, diagnostics, and  biomarkers of autoimmune neuromuscular junction disorders, case reports describing the progression and treatment options for rare neurological conditions, and a summary of how the first year of the COVID-19 pandemic affects neurology residency programs in the United States.

Staff Spotlight: Jeison Valencia

Jeison Valencia has been inspired to pursue science and laboratory research since age 7, after he watched an episode of the Powerpuff Girls, in which a scientist creates the three female superheroes. Now, as a member of the Chiba-Falek lab, the lab technician is performing analyses on brain tissue to better understand the roots of Alzheimer’s and other neurodegenerative conditions.

Duke Neurology Research Round Up, December 2021

Members of the Duke Neurology Department contributed to 14 new peer-reviewed journal articles written this November. Highlights include an analysis of fragmentation within the delivery of neurological health care, an examination of racial disparities in the use of telehealth, and a discussion of the best ways to use social medicine to share news on epilepsy and clinical neurophysiology. Read the paragraphs below for short summaries of each of these 14 articles, as well as links to the original entries themselves.

Memory Disorders

Duke Neurology Research Round Up, November 2021

This October, members of the Duke Neurology Department contributed to 12 new peer-reviewed journal articles, advancing our understanding of Alzheimer’s disease, stroke, chronic pain, and other conditions. These articles include discussions of the best framework for neuroscience curricula for medical students, the discovery of an existing experimental drug which offers a new avenue for treating pain without potential addiction issues, and an examination of the viability of ketogenic diets as an alternative treatment for amyotrophic lateral sclerosis (ALS).

Staff Spotlight: Ashley Moore, MS, MA-T

Within the lab of Carlene Moore, PhD, Ashley Moore, MS, MAT, (no relation) does “a little bit of everything,” acting as a lab manager, performing western blots, teaching and guiding undergraduate research students and more--and that’s just how she likes it. For this week’s Spotlight interview, Moore talks to us about this work, how her five years of experience as a public school teacher inform her work, and loving concerts and baking for family and friends when she’s not at work.