News

Members of the Duke Neurology Department contributed to seventeen peer-reviewed research studies published this August. Members of the lab of Nicole Calakos, MD, PhD, discovered that a medication created to treat patients with HIV may help people with dystonia. New translational research provided the most accurate atlas of the mouse model to date and answered questions about late-onset Alzheimer’s disease.

The American Association of Medical Colleges (AAMC) has awarded Leonard White, PhD, the 2021 Alpha Omega Alpha Robert J. Glaser Distinguished Teacher Award. These national awards, given to only four individuals a year, recognize outstanding contributions to medical education made by gifted teachers.

This July, new research from the Duke Neurology Department answered questions about the subcellular origins of itching, how COVID-19 is affecting people with amyotrophic lateral sclerosis, what factors influence people eligible for epilepsy surgery to move forward with the procedure and topics. The paragraphs below summarize the 11 articles appearing in peer-reviewed publications from our faculty, staff, and trainees. Check them out and find links to the original publications below.

Neuromuscular Disease

New publications written by members of the Duke Neurology Department published this June advanced our understanding of the origins of Alzheimer’s disease, stroke, and spinal injuries, as well as offering new insights on how to better diagnose and treat these and other conditions. Our faculty contributed to recent articles in Lancet Neurology, Stroke, and other high-impact journals. Read more about each of these stories, and find links to the original articles themselves, in the paragraphs below.
 

Neuromuscular Disease

Members of the Duke Neurology Department did their part for Stroke Awareness Month, contributing to eight new peer-reviewed studies published this May. But our other divisions didn’t hold back either, with thirteen other articles advancing our understanding of neuro-oncology, multiple sclerosis, headache, and other subjects.

Read about each of the studies published from members of the Duke Neurology Department below, and find links to the original journal articles as well.

Stroke

Members of the Duke Neurology Department advanced the fields of clinical, translational, and basic neuroscience this April with 14 new peer-reviewed studies. Nicole Calakos, MD, PhD, was the senior author of a new study in Science that  expands our understanding of the integrated stress response in the brain and how it influences learning and memory.

Daniel Gingerich joined the laboratory of Ornit Chiba-Falek, PhD, last year, exactly two days before the COVID-19 pandemic forced a campus-wide shut down, forcing him to learn a new set of technical skills from home. Since then Gingerich has become proficient in single-cell data analysis, and is using those techniques to better understand genetic and epigenetic dysregulation in late onset Alzheimer's disease.

Abbie Suttle, MSc, wants to improve our understanding of pain. In the lab of Yong Chen, PhD, she is currently working on two projects, the first to better understand the  trigeminal ganglion to potentially treat a painful jaw disorder known as TMD, and another to better understand and prevent the sensitization process that makes medications for migraine and headache less effective over the long term. In this week’s Spotlight interview, Suttle talks to us about her involvement in both of these projects.

Members of the Duke Neurology Department contributed to 21 new studies in peer-reviewed journals this March, advancing our ability to understand, treat, and prevent diseases and conditions from across the field of neurology. Brian Mac Grory, MB BCh, MRCP, and other members of our stroke and vascular neurology helped answer questions about the best way to treat patients who have a stroke in their sleep.

Research from members of the Duke Neurology Department advanced the fields of clinical, translational, and basic neurology in February. Over the past 28 days, our faculty, staff, and trainees contributed to journal articles answering questions about the use of mobile phones for stroke care, modifiable risk factors associated with cognitive decline in Parkinson’s, the genetics of Alzheimer’s disease, and more.