News

New research from the Duke Neurology Department provided insights into our ability to improve patient care and better understand neurological conditions. The 11 studies featuring our faculty, staff, and trainees published this September include the discovery of an HIV medication’s surprising potential to treat dystonia, an analysis of brain tumor patients admitted to intensive care, and a personal story of one faculty member’s grandfather, who lived through the ups and downs of a century of health care in the United States.

Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer’s Disease Research Center (ADRC), part of a federally-funded national network of similar centers.

Members of the Duke Neurology Department contributed to seventeen peer-reviewed research studies published this August. Members of the lab of Nicole Calakos, MD, PhD, discovered that a medication created to treat patients with HIV may help people with dystonia. New translational research provided the most accurate atlas of the mouse model to date and answered questions about late-onset Alzheimer’s disease.

Jeanne Caldwell didn’t have Alzheimer’s disease, yet she knew firsthand the devastation it can cause. For 11 years she cared for her mother who had the disease. After her mother’s death in 2015, Caldwell was determined to do what she could to make sure other families did not have to endure the hardships of caring for a loved one with Alzheimer’s.

Over 800 scientists from across the United States and overseas convened virtually for a joint Duke/UNC Alzheimer’s Disease Symposium examining how microbes and inflammation influence Alzheimer’s disease. The full-day event, held on May 27, shed light on the critical role that microbes and inflammation may play in how this disease develops and progresses.

Deborah Koltai, PhD, (Associate Professor in Psychiatry & Behavioral Sciences and Neurology, School of Medicine) and Jason Somarelli, PhD (Assistant Professor in Medicine, School of Medicine) are the winners of the 2021 Bass Connections Leadership Award.

Members of the Duke Neurology Department contributed to 21 new studies in peer-reviewed journals this March, advancing our ability to understand, treat, and prevent diseases and conditions from across the field of neurology. Brian Mac Grory, MB BCh, MRCP, and other members of our stroke and vascular neurology helped answer questions about the best way to treat patients who have a stroke in their sleep.

The final month of 2020 saw fifteen new publications written or co-written by members of the Duke Department of Neurology. Sneha Mantri, MD, MS, was a lead author of a new study examining factors contributing to burnout and moral injury among health-care workers at Duke. Our Neuromuscular Disease faculty wrote multiple studies advancing our understanding of myasthenia gravis, including how the COVID-19 pandemic is affecting people with this condition. Other articles answered questions about stroke, Parkinson’s, and other diseases.

This November, research from members of the Duke Department of Neurology examined how different types of seizures feel to the person experiencing them, discovered genes associated with longevity and health cognition, analyzed how the COVID-19 outbreak impacted stroke care, and more. Our faculty, trainees, and staff contributed to 15 studies published in the past 30 days. Read about each of them, and find links to the original articles below.    Multiple Sclerosis and Neuroimmunology

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study by Andy Liu, MD, James Burke, MD, PhD, and colleagues across Duke University. The novel computer software looks at retinal structure and blood vessels on images of the inside of the eye that have been correlated with cognitive changes.