News

Jeanne Caldwell didn’t have Alzheimer’s disease, yet she knew firsthand the devastation it can cause. For 11 years she cared for her mother who had the disease. After her mother’s death in 2015, Caldwell was determined to do what she could to make sure other families did not have to endure the hardships of caring for a loved one with Alzheimer’s.

Over 800 scientists from across the United States and overseas convened virtually for a joint Duke/UNC Alzheimer’s Disease Symposium examining how microbes and inflammation influence Alzheimer’s disease. The full-day event, held on May 27, shed light on the critical role that microbes and inflammation may play in how this disease develops and progresses.

Deborah Koltai, PhD, (Associate Professor in Psychiatry & Behavioral Sciences and Neurology, School of Medicine) and Jason Somarelli, PhD (Assistant Professor in Medicine, School of Medicine) are the winners of the 2021 Bass Connections Leadership Award.

Members of the Duke Neurology Department contributed to 21 new studies in peer-reviewed journals this March, advancing our ability to understand, treat, and prevent diseases and conditions from across the field of neurology. Brian Mac Grory, MB BCh, MRCP, and other members of our stroke and vascular neurology helped answer questions about the best way to treat patients who have a stroke in their sleep.

The final month of 2020 saw fifteen new publications written or co-written by members of the Duke Department of Neurology. Sneha Mantri, MD, MS, was a lead author of a new study examining factors contributing to burnout and moral injury among health-care workers at Duke. Our Neuromuscular Disease faculty wrote multiple studies advancing our understanding of myasthenia gravis, including how the COVID-19 pandemic is affecting people with this condition. Other articles answered questions about stroke, Parkinson’s, and other diseases.

This November, research from members of the Duke Department of Neurology examined how different types of seizures feel to the person experiencing them, discovered genes associated with longevity and health cognition, analyzed how the COVID-19 outbreak impacted stroke care, and more. Our faculty, trainees, and staff contributed to 15 studies published in the past 30 days. Read about each of them, and find links to the original articles below. 

Multiple Sclerosis and Neuroimmunology

A form of artificial intelligence designed to interpret a combination of retinal images was able to successfully identify a group of patients who were known to have Alzheimer’s disease, suggesting the approach could one day be used as a predictive tool, according to an interdisciplinary study by Andy Liu, MD, James Burke, MD, PhD, and colleagues across Duke University. The novel computer software looks at retinal structure and blood vessels on images of the inside of the eye that have been correlated with cognitive changes.

Members of the Duke Neurology Department contributed to 14 new peer-reviewed studies this October, advancing our understanding of or ability to treat Parkinson’s disease, Alzheimer’s, stroke, and other conditions. Laurie Sanders, PhD, and Claudia Gonzalez Hunt, PhD, advanced our understanding of the links between mitochondrial DNA damage and Parkinson’s disease, providing a potential avenue for future therapies.

This September, members of the Duke Neurology Department contributed to 26 new studies, advancing our knowledge of neuroscience at the subcellular, national, and global levels. Ornit Chiba-Falek, PhD, and Laurie Sanders, PhD, lead studies that answered questions about the genetic origins of Parkinson’s disease and its connection to some forms of breast cancer.

One year after coming to our Morreene Road Clinic, Crystal Ballard still enjoys the challenges and opportunities that come with her work. Each day her job involves supporting our neurology providers, supervising staff assistants, preparing patients for clinic and other tasks. For this week’s “Spotlight” interview, Ballard talks to us about this work, her various positions at Duke over the past 20 years, and embracing and adapting to the challenges brought on by the COVID-19 pandemic.